What causes sickle cell anemia

[Stunna]

Sickle cell anemia is a genetic disorder caused by a mutation in the hemoglobin gene. Hemoglobin is the protein in red blood cells that carries oxygen throughout the body. In people with sickle cell anemia, the mutated gene leads to the production of abnormal hemoglobin molecules, which can cause the red blood cells to take on a sickle or crescent shape.

The sickle-shaped red blood cells can get stuck in small blood vessels, leading to reduced blood flow and oxygen supply to organs and tissues. This can cause a range of symptoms, including fatigue, pain, organ damage, and increased risk of infections.

Sickle cell anemia is an inherited condition, which means that it is passed down from parents to their children through genes. To develop sickle cell anemia, a person must inherit two copies of the mutated gene, one from each parent. People who inherit only one copy of the mutated gene are carriers of the disease but typically do not develop symptoms.

Sickle cell anemia is more common in people of African descent, but it can also occur in people of Hispanic, Middle Eastern, and Mediterranean descent.

Sickle cells have a shorter lifespan than normal red blood cells, which can lead to a shortage of red blood cells in the body, causing anemia.

The sickle-shaped cells can get stuck in small blood vessels, blocking blood flow and causing pain. These episodes are called pain crises and can be very severe.

Sickle cells can also block blood flow to organs, which can cause damage to the liver, spleen, kidneys, and other organs..

 

[Jake1972]

Sickle cell anemia is caused by a mutation in the gene that codes for the protein hemoglobin. This mutation causes the hemoglobin to become abnormally shaped, leading to the formation of sickle-shaped red blood cells. This mutation is inherited in an autosomal recessive pattern, which means that both parents must be carriers of the mutation in order for the child to develop the condition.

 

[coincash08]

Sickle cell is a disease caused by genotype.If a man with genotype xx marries a woman with gentype xx,their children with suffer sicle cell anaemia.

 

[Yusra3]

Sickle cell anemia is the most common inherited blood disorder in the United States. It is caused by a mutation in one of the genes that make hemoglobin, which carries oxygen from your lungs to other parts of your body. This mutation causes sickle red blood cells, which deform easily and can block blood flow in your body.

Sickle cells are abnormal cells that have a sickle shape when they divide. The mutation increases the number of these abnormal cells, which can cause severe damage to tissues and organs when they block blood flow.

Inherited conditions like sickle cell anemia may be passed down through families. Having a family history of sickle cell anemia increases the risk that you will inherit one of these mutations from your parents or siblings, who have been carriers for many generations. If one parent has sickle cell anemia, there is a 25% chance that their child will have it as well (even if they are not carriers).