Angina and Myoca(r)dial Infraction

Definition: This is a clinical condition that results from abrupt reduction in coronary blood flow due to thrombic occlusion artery leading to necrosis and death of myocardium supplied by the coronary artery. This is a very serious medical emergency with 50% mortality within two hours of onset of symptoms. And further, 40% mortality in first four weeks.

Angina and Myocardial Infarction usually follows rupture of an antheromatous plaque with superadded thrombus. Rupture of at hero may us plaque exposes collager fibres to the circulation with consequent activation of platelet and initiation if the coagulation cascade. The ultimate outcome of this is acute coronary artery occlusion.

Systoms
These are some of the symptoms of Angina and Myocardial Infarction;
Sudden retrosternal chest pain of less than 20 minutes duration associated with nausea, excessive sweating, dyspnoea, palpitations.

Chest pain may be present especially in the elderly and diabetic.

Patients with silent MI may present with syncope, pulmonary oedema, vomiting and dyspeptic symptoms, acute confusional state, stroke, diabetic ketoacidosis (DKA) or hyperosmolar non-ketotic (HONK) states.

Treatment
Patients should me admited and if possible, to the intensive care unit.

Patients should be given absolute bed rest

Immediate pain and anxiety relief would help in reducing pain felt

Secure intravenous access

Oxygen (60%-100%) by face masks should be given to patients to enhance breathing.
 
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